MSH2 recombinant monoclonal antibody, clone R04-8B4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human MSH2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human MSH2
Theoretical MW (kDa)
Calculated MW: 105 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of MSH2 in rat Brain, CHO-K1, Hela lysates using human MSH2 recombinant monoclonal antibody, clone R04-8B4 (Cat # RAB01701). -
Gene Info — MSH2
Entrez GeneID
4436Protein Accession#
P43246Gene Name
MSH2
Gene Alias
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Gene Description
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Gene Ontology
HyperlinkGene Summary
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq
Other Designations
mutS homolog 2
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Interactome
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Disease
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