ITGA2B recombinant monoclonal antibody, clone R01-1C2
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More Files
- More Functions
Western Blot
Western blot analysis of CD41 in C6, Hela lysates using human Integrin alpha IIb recombinant monoclonal antibody, clone R01-1C2 (Cat # RAB01682).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human CD41.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CD41
Theoretical MW (kDa)
Calculated MW: 113 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of CD41 in C6, Hela lysates using human Integrin alpha IIb recombinant monoclonal antibody, clone R01-1C2 (Cat # RAB01682). -
Gene Info — ITGA2B
Entrez GeneID
3674Protein Accession#
P08514Gene Name
ITGA2B
Gene Alias
CD41, CD41B, GP2B, GPIIb, GTA, HPA3
Gene Description
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Gene Ontology
HyperlinkGene Summary
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq
Other Designations
integrin alpha 2b|platelet fibrinogen receptor, alpha subunit|platelet-specific antigen BAK
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Interactome
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Pathway
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Disease
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