ANGPT2 recombinant monoclonal antibody, clone R04-7E6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Angiopoietin 2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Angiopoietin 2
Theoretical MW (kDa)
Calculated MW: 57 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Angiopoietin 2 in rat Brain lysates using human Angiopoietin 2 recombinant monoclonal antibody, clone R04-7E6 (Cat # RAB01607).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — ANGPT2
Entrez GeneID
285Protein Accession#
O15123Gene Name
ANGPT2
Gene Alias
AGPT2, ANG2
Gene Description
angiopoietin 2
Omim ID
601922Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
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Interactome
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Disease
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