AP3M1 recombinant monoclonal antibody, clone R08-8D2
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More Files
- More Functions
Western Blot
Western blot analysis of AP3M1 in K562, C6, 3T3, Hela lysates using human AP3M1 recombinant monoclonal antibody, clone R08-8D2 (Cat # RAB01601).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human AP3M1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human AP3M1
Theoretical MW (kDa)
Calculated MW: 47 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of AP3M1 in K562, C6, 3T3, Hela lysates using human AP3M1 recombinant monoclonal antibody, clone R08-8D2 (Cat # RAB01601). -
Gene Info — AP3M1
Entrez GeneID
26985Protein Accession#
Q9Y2T2Gene Name
AP3M1
Gene Alias
MGC22164
Gene Description
adaptor-related protein complex 3, mu 1 subunit
Omim ID
610366Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
Other Designations
AP-3 adapter complex mu3A subunit|OTTHUMP00000019859|OTTHUMP00000019860|clathrin adaptor complex AP3, mu-3A subunit|mu-adaptin 3A
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Interactome
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Pathway
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Disease
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