APTX recombinant monoclonal antibody, clone R03-9F6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Aprataxin.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Aprataxin
Theoretical MW (kDa)
Calculated MW: 41 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence(1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Aprataxin in K562, Hela lysates using human Aprataxin recombinant monoclonal antibody, clone R03-9F6 (Cat # RAB01596).Immunocytochemistry
Immunocytochemistry analysis of Aprataxin (green) in U87-MG using human Aprataxin recombinant monoclonal antibody, clone R03-9F6 (Cat # RAB01596), and DAPI(blue). -
Gene Info — APTX
Entrez GeneID
54840Protein Accession#
Q7Z2E3Gene Name
APTX
Gene Alias
AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, FLJ20157, MGC1072
Gene Description
aprataxin
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000021188|ataxia 1, early onset with hypoalbuminemia
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Interactome
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Disease
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