GPX1 recombinant monoclonal antibody, clone R06-0H1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human GPX1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human GPX1.
Theoretical MW (kDa)
Calculated MW: 22 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4, (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Glutathione Peroxidase 1 in A549, HL-60 lysates using Glutathione Peroxidase 1 antibody.Immunocytochemistry
Immunocytochemistry staining of HeLa cells with GPX1 recombinant monoclonal antibody, clone R06-0H1 (Cat # RAB01442).Immunofluorescence
Immunoprecipitation
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Gene Info — GPX1
Entrez GeneID
2876Protein Accession#
P07203Gene Name
GPX1
Gene Alias
GSHPX1, MGC14399, MGC88245
Gene Description
glutathione peroxidase 1
Omim ID
138320Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
cellular glutathione peroxidase
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Interactome
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Pathway
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