UBA3 recombinant monoclonal antibody, clone R05-6C8
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More Files
- More Functions
Western Blot
Western Blot analysis of Hela, A549, HL-60 lysates with UBA3 recombinant monoclonal antibody, clone R05-6C8 (Cat # RAB01340).
Western Blot
Western Blot analysis of Raw 264.7 cells with UBA3 recombinant monoclonal antibody, clone R05-6C8 (Cat # RAB01340).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human UBA3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human UBA3.
Theoretical MW (kDa)
Calculated MW: 52 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4, (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Hela, A549, HL-60 lysates with UBA3 recombinant monoclonal antibody, clone R05-6C8 (Cat # RAB01340).Western Blot
Western Blot analysis of Raw 264.7 cells with UBA3 recombinant monoclonal antibody, clone R05-6C8 (Cat # RAB01340). -
Gene Info — UBA3
Entrez GeneID
9039Protein Accession#
Q8TBC4Gene Name
UBA3
Gene Alias
DKFZp566J164, MGC22384, UBE1C, hUBA3
Gene Description
ubiquitin-like modifier activating enzyme 3
Omim ID
603172Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
Nedd8-activating enzyme hUba3|UBA3, ubiquitin-activating enzyme E1 homolog|ubiquitin-activating enzyme 3|ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)|ubiquitin-activating enzyme E1C (homologous to yeast UBA3)
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Interactome
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Pathway
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