SQSTM1 recombinant monoclonal antibody, clone R08-4H8
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More Files
- More Functions
Immunocytochemistry
Immunocytochemistry analysis of SQSTM1/p62 (green) in U87-MG using SQSTM1/p62 antibody,and DAPI(blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SQSTM1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human SQSTM1/p62.
Theoretical MW (kDa)
Calculated MW: 48 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine pH 7.4 (0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
Immunocytochemistry analysis of SQSTM1/p62 (green) in U87-MG using SQSTM1/p62 antibody,and DAPI(blue).Immunofluorescence
Immunoprecipitation
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Gene Info — SQSTM1
Entrez GeneID
8878Protein Accession#
Q13501Gene Name
SQSTM1
Gene Alias
A170, OSIL, PDB3, ZIP3, p60, p62, p62B
Gene Description
sequestosome 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq
Other Designations
EBI3-associated protein p60|Paget disease of bone 3|oxidative stress induced like|phosphotyrosine independent ligand for the Lck SH2 domain p62|ubiquitin-binding protein p62
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Interactome
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Disease
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