MALT1 polyclonal antibody
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of human MALT1 in E coli. , using MALT1 polyclonal antibody (Cat # PAB8476) .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MALT1.
Immunogen
A synthetic peptide corresponding to human MALT1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis of human MALT1 in E coli. , using MALT1 polyclonal antibody (Cat # PAB8476) . -
Gene Info — MALT1
Entrez GeneID
10892Gene Name
MALT1
Gene Alias
DKFZp434L132, MLT, MLT1
Gene Description
mucosa associated lymphoid tissue lymphoma translocation gene 1
Omim ID
604860Gene Ontology
HyperlinkGene Summary
This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
MALT associated translocation|MALT-lymphoma associated translocation|caspase-like protein|mucosa associated lymphoid tissue lymphoma translocation protein 1|paracaspase
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Interactome
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Pathway
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Disease
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Publication Reference
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Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.
Lucas PC, Yonezumi M, Inohara N, McAllister-Lucas LM, Abazeed ME, Chen FF, Yamaoka S, Seto M, Nunez G.
The Journal of Biological Chemistry 2001 Jun; 276(22):19012.
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It's got you covered. NF-kappaB in the epidermis.
Kaufman CK, Fuchs E.
The Journal of Cell Biology 2000 May; 149(5):999.
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IKK1-deficient mice exhibit abnormal development of skin and skeleton.
Li Q, Lu Q, Hwang JY, Buscher D, Lee KF, Izpisua-Belmonte JC, Verma IM.
Genes & Development 1999 May; 13(10):1322.
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Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
Willis TG, Jadayel DM, Du MQ, Peng H, Perry AR, Abdul-Rauf M, Price H, Karran L, Majekodunmi O, Wlodarska I, Pan L, Crook T, Hamoudi R, Isaacson PG, Dyer MJ.
Cell 1999 Jan; 96(1):35.
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Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.
Seitz CS, Lin Q, Deng H, Khavari PA.
PNAS 1998 Mar; 95(5):2307.
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Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.
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