FZD4 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
FZD4 polyclonal antibody (Cat # PAB7551) (1 ug/mL) staining of small intestine (ileum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FZD4.
Immunogen
A synthetic peptide corresponding to human FZD4.
Sequence
DEEERRCDPIRIS
Host
Goat
Theoretical MW (kDa)
59.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FZD4 polyclonal antibody (Cat # PAB7551) (1 ug/mL) staining of small intestine (ileum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FZD4
Entrez GeneID
8322Protein Accession#
NP_036325.2Gene Name
FZD4
Gene Alias
CD344, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390
Gene Description
frizzled homolog 4 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq
Other Designations
WNT receptor frizzled-4|exudative vitreoretinopathy 1 (autosomal dominant; Criswick-Schepens syndrome)|frizzled 4
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Interactome
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Pathway
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Disease
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Publication Reference
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Wnt pathway-related gene expression in inflammatory bowel disease.
You J, Nguyen AV, Albers CG, Lin F, Holcombe RF.
Digestive Diseases and Sciences 2008 Apr; 53(4):1013.
Application：Microarray, Human, Normal, uninflamed IBD, inflamed IBD colonic mucosa.
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Wnt pathway-related gene expression in inflammatory bowel disease.
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