TRPV5 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TRPV5.
Immunogen
A synthetic peptide corresponding to internal region of human TRPV5.
Sequence
C-SHRGWEILRQNT
Host
Goat
Theoretical MW (kDa)
82.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TRPV5 polyclonal antibody (Cat # PAB7467) (1 ug/mL) staining of human pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunocytochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRPV5
Entrez GeneID
56302Protein Accession#
NP_062815.2Gene Name
TRPV5
Gene Alias
CAT2, ECAC1, OTRPC3
Gene Description
transient receptor potential cation channel, subfamily V, member 5
Omim ID
606679Gene Ontology
HyperlinkGene Summary
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq
Other Designations
calcium transporter 2|epithelial calcium channel 1|osm-9-like TRP channel 3
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Interactome
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Publication Reference
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The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.
van der Eerden BC, Hoenderop JG, de Vries TJ, Schoenmaker T, Buurman CJ, Uitterlinden AG, Pols HA, Bindels RJ, van Leeuwen JP.
PNAS 2005 Nov; 102(48):17507.
Application:ICC, WB-Ce, Mouse, Osteoclasts.
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The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.
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