DAO polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DAO.
Immunogen
A synthetic peptide corresponding to human DAO.
Sequence
C-EEKKLSRMPPSH
Host
Goat
Theoretical MW (kDa)
39.5
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — DAO
Entrez GeneID
1610Protein Accession#
NP_001908.3Gene Name
DAO
Gene Alias
DAAO, DAMOX, MGC35381, OXDA
Gene Description
D-amino-acid oxidase
Gene Ontology
HyperlinkGene Summary
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia.
Corvin A, Donohoe G, McGhee K, Murphy K, Kenny N, Schwaiger S, Nangle JM, Morris D, Gill M.
Neuroscience Letters 2007 Oct; 426(2):97.
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D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia.
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