NKD2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NKD2.
Immunogen
A synthetic peptide corresponding to human NKD2.
Sequence
C-HKRYRQKGREGHS
Host
Goat
Theoretical MW (kDa)
50.1
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — NKD2
Entrez GeneID
85409Protein Accession#
NP_149111.1Gene Name
NKD2
Gene Alias
Naked2
Gene Description
naked cuticle homolog 2 (Drosophila)
Omim ID
607852Gene Ontology
HyperlinkGene Summary
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM
Other Designations
Dvl-binding protein NKD2|naked cuticle homolog 2|naked cuticle-2
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Pathway
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Publication Reference
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Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.
Zhang S, Cagatay T, Amanai M, Zhang M, Kline J, Castrillon DH, Ashfaq R, Oz OK, Wharton KA Jr.
Molecular and Cellular Biology 2007 Jun; 27(12):4454.
Application:WB-Ti, Mouse , Mouse embryos.
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Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.
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