PTBP2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PTBP2.
Immunogen
A synthetic peptide corresponding to human PTBP2.
Sequence
C-SKKFKGEDKMD
Host
Goat
Theoretical MW (kDa)
57.5
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PTBP2
Entrez GeneID
58155Protein Accession#
NP_067013.1Gene Name
PTBP2
Gene Alias
FLJ34897, PTB, PTBLP, brPTB, nPTB, nPTB5, nPTB6, nPTB7, nPTB8
Gene Description
polypyrimidine tract binding protein 2
Omim ID
608449Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain. [provided by RefSeq
Other Designations
OTTHUMP00000012411|PTB-like|neural polypyrimidine tract binding protein|splicing regulator
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Interactome
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Disease
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Publication Reference
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A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.
Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M Jr, Black DL.
Genes & Development 2007 Jul; 21(13):1636.
Application：IF, IHC-Fr, WB, Human, Mouse , HEK 293, Mouse brain, N1E, N2A, P19 cells.
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A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.
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