GPSM2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GPSM2.
Immunogen
A synthetic peptide corresponding to human GPSM2.
Sequence
C-NRLKGKKYKTNSSTK
Host
Goat
Theoretical MW (kDa)
75.8
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Immunohistochemistry(5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
GPSM2 polyclonal antibody (Cat # PAB7195) (5 ug/mL) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPSM2
Entrez GeneID
29899Protein Accession#
NP_0.37428.2Gene Name
GPSM2
Gene Alias
LGN, Pins
Gene Description
G-protein signaling modulator 2 (AGS3-like, C. elegans)
Omim ID
609245Gene Ontology
HyperlinkGene Summary
Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 belongs to a group of proteins that modulate activation of G proteins (Blumer et al., 2002 [PubMed 11832491]).[supplied by OMIM
Other Designations
G-protein signalling modulator 2 (AGS3-like, C. elegans)|LGN protein
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Interactome
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Disease
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Publication Reference
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Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.
Yasumi M, Sakisaka T, Hoshino T, Kimura T, Sakamoto Y, Yamanaka T, Ohno S, Takai Y.
The Journal of Biological Chemistry 2005 Feb; 280(8):6761.
Application:IF, IP-WB, WB-Ce, WB-Tr, Human, HEK293 cells.
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Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division.
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