PDE4D polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PDE4D.
Immunogen
A synthetic peptide corresponding to N-terminus of human PDE4D.
Sequence
HVNNFPFRRHS-C
Host
Goat
Theoretical MW (kDa)
76.5
Reactivity
Rat
Specificity
This antibody is expected to recognize isoform 3 (AAA97892.1) only.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
PDE4D polyclonal antibody (Cat # PAB7166) (0.01 ug/mL) staining of rat brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PDE4D
Entrez GeneID
5144Protein Accession#
AAA97892.1Gene Name
PDE4D
Gene Alias
DPDE3, HSPDE4D, PDE4DN2, STRK1
Gene Description
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins
Other Designations
cAMP-specific phosphodiesterase 4D|cAMP-specific phosphodiesterase PDE4D6|dunce-like phosphodiesterase E3|phosphodiesterase 4D, cAMP-specific (dunce
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
Houslay MD, Baillie GS, Maurice DH.
Circulation Research 2007 Apr; 100(7):950.
-
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com