SDCBP polyclonal antibody
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More Files
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Western Blot (Cell lysate)
SDCBP polyclonal antibody (Cat # PAB7132) (0.01 ug/mL) staining of human HEK293 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SDCBP.
Immunogen
A synthetic peptide corresponding to human SDCBP.
Sequence
SLEDLKVDKVIQAQ-C
Host
Goat
Theoretical MW (kDa)
32.4, 32.3
Reactivity
Human
Specificity
This antibody is expected to recognize isoform 1 (NP_005616.2 and NP_001007068.1) and isoform 3 (NP_001007070.1and NP_001007071.1) only.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
SDCBP polyclonal antibody (Cat # PAB7132) (0.01 ug/mL) staining of human HEK293 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SDCBP
Entrez GeneID
6386Protein Accession#
NP_005616.2;NP_001007068.1;NP_001007069;NP_001007070.1;NP_001007071.1Gene Name
SDCBP
Gene Alias
MDA-9, ST1, SYCL, TACIP18
Gene Description
syndecan binding protein (syntenin)
Omim ID
602217Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
melanoma differentiation associated protein-9|pro-TGF-alpha cytoplasmic domain-interacting protein 18|scaffold protein Pbp1|syntenin
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Interactome
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Publication Reference
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Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism.
Jiang C, Hopfner F, Katsikoudi A, Hein R, Catli C, Evetts S, Huang Y, Wang H, Ryder JW, Kuhlenbaeumer G, Deuschl G, Padovani A, Berg D, Borroni B, Hu MT, Davis JJ, Tofaris GK.
Journal of Neurology, Neurosurgery, and Psychiatry 2020 Jul; 91(7):720.
Application：Electrochemiluminescence, Recombinant protein.
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Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63.
Latysheva N, Muratov G, Rajesh S, Padgett M, Hotchin NA, Overduin M, Berditchevski F.
Molecular Biology of the Cell 2006 Oct; 26(20):7707.
Application：WB, Human, MDA-MB-231 cells.
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Serum neuronal exosomes predict and differentiate Parkinson's disease from atypical parkinsonism.
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