STMN1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
STMN1 polyclonal antibody (Cat # PAB6964) (1 ug/mL) staining of human testis Lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of STMN1.
Immunogen
A synthetic peptide corresponding to C-terminus of human STMN1.
Sequence
C-KNKESKDPADETEAD
Host
Goat
Theoretical MW (kDa)
17.3
Reactivity
Human, Mouse
Specificity
The three reported isoforms (NP_005554.1, NP_981944.1 and NP_981946.1) represent identical protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:1000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
STMN1 polyclonal antibody (Cat # PAB6964) (1 ug/mL) staining of human testis Lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — STMN1
Entrez GeneID
3925Protein Accession#
NP_005554.1;NP_981944.1;NP_981946.1Gene Name
STMN1
Gene Alias
LAP18, Lag, OP18, PP17, PP19, PR22, SMN
Gene Description
stathmin 1/oncoprotein 18
Omim ID
151442Gene Ontology
HyperlinkGene Summary
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000008527|OTTHUMP00000008528|OTTHUMP00000008530|leukemia-associated phosphoprotein p18|metablastin|oncoprotein 18|phosphoprotein 19|prosolin|stathmin 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene.
Miyashita H, Kanemura M, Yamazaki T, Abe M, Sato Y.
Arteriosclerosis, Thrombosis, and Vascular Biology 2004 May; 24(5):878.
Application：WB, Human, MSS31 cells.
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Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene.
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