NEUROD2 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of NEUROD2.
Immunogen
A synthetic peptide corresponding to human NEUROD2.
Sequence
C-DMHLHHDRGPMYEE
Host
Goat
Theoretical MW (kDa)
41.4
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — NEUROD2
Entrez GeneID
4761Protein Accession#
NP_006151.3Gene Name
NEUROD2
Gene Alias
MGC26304, NDRF, bHLHa1
Gene Description
neurogenic differentiation 2
Omim ID
601725Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq
Other Designations
neuroD-related factor|neurogenic basic-helix-loop-helix protein|neurogenic differentiation factor 2
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Interactome
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Disease
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Publication Reference
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The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning.
Lin CH, Hansen S, Wang Z, Storm DR, Tapscott SJ, Olson JM.
PNAS 2005 Oct; 102(41):14877.
Application:ChIP, Mouse, Primary neuronal culture from mouse brains.
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The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning.
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