RTN4R polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RTN4R.
Immunogen
A synthetic peptide corresponding to human RTN4R.
Sequence
C-LQALPDDTFRDLGN
Host
Goat
Theoretical MW (kDa)
50.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
RTN4R polyclonal antibody (Cat # PAB6793) (0.3 ug/mL) staining of human brain lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RTN4R
Entrez GeneID
65078Protein Accession#
NP_075380.1Gene Name
RTN4R
Gene Alias
NGR, NOGOR
Gene Description
reticulon 4 receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq
Other Designations
Nogo-66 receptor|UNQ330/PRO526|nogo receptor
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Interactome
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Disease
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Publication Reference
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TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.
Shao Z, Browning JL, Lee X, Scott ML, Shulga-Morskaya S, Allaire N, Thill G, Levesque M, Sah D, McCoy JM, Murray B, Jung V, Pepinsky RB, Mi S.
Neuron 2005 Feb; 45(3):353.
Application:IP, IP-WB, Monkey, COS-7 cells.
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TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.
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