RGS17 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RGS17.
Immunogen
A synthetic peptide corresponding to human RGS17.
Sequence
C-SFVESTAGSSSES
Host
Goat
Theoretical MW (kDa)
24.4
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — RGS17
Entrez GeneID
26575Protein Accession#
NP_036551Gene Name
RGS17
Gene Alias
RGS-17, RGSZ2, hRGS17
Gene Description
regulator of G-protein signaling 17
Omim ID
607191Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq
Other Designations
OTTHUMP00000017460|regulator of G-protein signalling 17
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Interactome
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Disease
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Publication Reference
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Inactivation of Galpha(z) causes disassembly of the Golgi apparatus.
Nagahama M, Usui S, Shinohara T, Yamaguchi T, Tani K, Tagaya M.
Journal of Cell Science 2002 Dec; 115(Pt 23):4483.
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Inactivation of Galpha(z) causes disassembly of the Golgi apparatus.
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