ARAP1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ARAP1.
Immunogen
A synthetic peptide corresponding to C-terminus of human ARAP1.
Sequence
C-AFTADPLSLLRNV
Host
Goat
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ARAP1
Entrez GeneID
116985Protein Accession#
NP_056057.2;NP_001035207.1;NP_001128662.1Gene Name
ARAP1
Gene Alias
CENTD2, KIAA0782
Gene Description
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Omim ID
606646Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1|centaurin, delta 2
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Interactome
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Pathway
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Publication Reference
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ARAP1: a point of convergence for Arf and Rho signaling.
Miura K, Jacques KM, Stauffer S, Kubosaki A, Zhu K, Hirsch DS, Resau J, Zheng Y, Randazzo PA.
Molecular Cell 2002 Jan; 9(1):109.
Application:IF, WB, Human, Mouse, Monkey, COS-7, HEK 293, HeLa, Jurkat, MDCK, NIH/3T3 cells.
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ARAP1: a point of convergence for Arf and Rho signaling.
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