CLDN14 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
CLDN14 polyclonal antibody (Cat # PAB6208) staining (1 ug/mL) of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CLDN14.
Immunogen
A synthetic peptide corresponding to C-terminus of human CLDN14.
Sequence
C-SATHSGYRLNDYV
Host
Goat
Theoretical MW (kDa)
25.7
Reactivity
Human, Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:128000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
CLDN14 polyclonal antibody (Cat # PAB6208) staining (1 ug/mL) of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CLDN14
Entrez GeneID
23562Protein Accession#
NP_036262.1Gene Name
CLDN14
Gene Alias
DFNB29
Gene Description
claudin 14
Omim ID
605608Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000109045|OTTHUMP00000109046|OTTHUMP00000109047|OTTHUMP00000109048|OTTHUMP00000109049
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.
Wilcox ER, Burton QL, Naz S, Riazuddin S, Smith TN, Ploplis B, Belyantseva I, Ben-Yosef T, Liburd NA, Morell RJ, Kachar B, Wu DK, Griffith AJ, Riazuddin S, Friedman TB.
Cell 2001 Jan; 104(1):165.
Application：IF, Mouse, Ear.
-
Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com