TPK1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with TPK1 polyclonal antibody (Cat # PAB31540) shows strong cytoplasmic positivity in trophoblastic cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human TPK1.
Immunogen
Recombinant protein corresponding to human TPK1.
Sequence
AFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGERESFLPEFINGDFDSI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with TPK1 polyclonal antibody (Cat # PAB31540) shows strong cytoplasmic positivity in trophoblastic cells. -
Gene Info — TPK1
Entrez GeneID
27010Protein Accession#
Q9H3S4Gene Name
TPK1
Gene Alias
HTPK1, PP20
Gene Description
thiamin pyrophosphokinase 1
Omim ID
606370Gene Ontology
HyperlinkGene Summary
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
placental protein 20|thiamine diphosphokinase|thiamine kinase|thiamine pyrophosphokinase 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway.
Mayr JA, Freisinger P, Schlachter K, Rolinski B, Zimmermann FA, Scheffner T, Haack TB, Koch J, Ahting U, Prokisch H, Sperl W.
American Journal of Human Genetics 2011 Dec; 89(6):806.
Application：WB-Ti, Human, Human muscle biopsy.
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Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway.
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