KRT76 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with KRT76 polyclonal antibody (Cat # PAB31531) shows strong positivity in stratum corneum.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human KRT76.
Immunogen
Recombinant protein corresponding to human KRT76.
Sequence
SGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQHSSTK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with KRT76 polyclonal antibody (Cat # PAB31531) shows strong positivity in stratum corneum. -
Gene Info — KRT76
Entrez GeneID
51350Protein Accession#
Q01546Gene Name
KRT76
Gene Alias
HUMCYT2A, KRT2B, KRT2P
Gene Description
keratin 76
Gene Ontology
HyperlinkGene Summary
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq
Other Designations
cytokeratin 2|keratin 2p
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Interactome
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Publication Reference
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Keratin 76 is required for tight junction function and maintenance of the skin barrier.
DiTommaso T, Cottle DL, Pearson HB, Schlüter H, Kaur P, Humbert PO, Smyth IM.
PLoS Genetics 2014 Oct; 10(10):e1004706.
Application：IF, IHC-Fr, WB-Ce, WB-Ti, Human, Mouse, A-549 cells, Mouse dorsal skin, Mouse face skin, Mouse paw pad.
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Keratin 76 is required for tight junction function and maintenance of the skin barrier.
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