MAPK8IP2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with MAPK8IP2 polyclonal antibody (Cat # PAB31182) shows distinct cytoplasmic positivity in tubular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human MAPK8IP2.
Immunogen
Recombinant protein corresponding to human MAPK8IP2.
Sequence
FSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEM
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with MAPK8IP2 polyclonal antibody (Cat # PAB31182) shows distinct cytoplasmic positivity in tubular cells. -
Gene Info — MAPK8IP2
Entrez GeneID
23542Protein Accession#
Q13387Gene Name
MAPK8IP2
Gene Alias
IB2, JIP2, PRKM8IPL
Gene Description
mitogen-activated protein kinase 8 interacting protein 2
Omim ID
607755Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq
Other Designations
JNK MAP kinase scaffold protein JIP2|JNK-interacting protein 2|PRKM8 interacting protein-like|homologous to mouse JIP-1|islet-brain 2
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Interactome
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Pathway
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