SENP2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with SENP2 polyclonal antibody (Cat # PAB31128) shows strong cytoplasmic positivity in exocrine glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human SENP2.
Immunogen
Recombinant protein corresponding to human SENP2.
Sequence
RRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with SENP2 polyclonal antibody (Cat # PAB31128) shows strong cytoplasmic positivity in exocrine glandular cells. -
Gene Info — SENP2
Entrez GeneID
59343Protein Accession#
Q9HC62Gene Name
SENP2
Gene Alias
AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2
Gene Description
SUMO1/sentrin/SMT3 specific peptidase 2
Omim ID
608261Gene Ontology
HyperlinkGene Summary
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM
Other Designations
SUMO1/sentrin/SMT3 specific protease 2|sentrin-specific protease
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Interactome
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Pathway
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Publication Reference
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Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung.
Wang J, Qian J, Hoeksema MD, Zou Y, Espinosa AV, Rahman SM, Zhang B, Massion PP.
Clinical Cancer Research 2013 Oct; 19(20):5580.
Application：WB-Ce, WB-Tr, Human, A-549, H23, H157, H520, H1648, H1819, H2882, HCC15, HCC95, SW900 cells.
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Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung.
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