PDLIM3 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with PDLIM3 polyclonal antibody (Cat # PAB30704) shows strong cytoplasmic positivity in myocytes.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human PDLIM3.
Immunogen
Recombinant protein corresponding to human PDLIM3.
Sequence
WGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skeletal muscle with PDLIM3 polyclonal antibody (Cat # PAB30704) shows strong cytoplasmic positivity in myocytes. -
Gene Info — PDLIM3
Entrez GeneID
27295Protein Accession#
Q53GG5Gene Name
PDLIM3
Gene Alias
ALP, DKFZp686L0362
Gene Description
PDZ and LIM domain 3
Omim ID
605889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
PDZ and LIM domain protein 3|alpha-actinin-2-associated LIM protein|enigma homolog
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Interactome
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Disease
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