NR4A2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NR4A2 polyclonal antibody (Cat # PAB30608) shows moderate membranous and nuclear positivity in cells in tubules.
Immunofluorescence
Immunofluorescent staining of SiHa cells with NR4A2 polyclonal antibody (Cat # PAB30608) (Green) shows positivity in nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human NR4A2.
Immunogen
Recombinant protein corresponding to human NR4A2.
Sequence
VQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NR4A2 polyclonal antibody (Cat # PAB30608) shows moderate membranous and nuclear positivity in cells in tubules.Immunofluorescence
Immunofluorescent staining of SiHa cells with NR4A2 polyclonal antibody (Cat # PAB30608) (Green) shows positivity in nucleus but excluded from the nucleoli. -
Gene Info — NR4A2
Entrez GeneID
4929Protein Accession#
P43354Gene Name
NR4A2
Gene Alias
HZF-3, NOT, NURR1, RNR1, TINUR
Gene Description
nuclear receptor subfamily 4, group A, member 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
NGFI-B/nur77 beta-type transcription factor homolog|T-cell nuclear receptor NOT|intermediate-early receptor protein|nur related protein-1, human homolog of|orphan nuclear receptor NURR1|transcriptionally inducible nuclear receptor related 1
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Interactome
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Disease
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