ICAM5 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with ICAM5 polyclonal antibody (Cat # PAB30568) shows distinct positivity in neuropil.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with ICAM5 polyclonal antibody (Cat # PAB30568) shows positivity in nucleus but excluded from the nucleoli. Antibody staining is shown in green.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ICAM5.
Immunogen
Recombinant protein corresponding to amino acids 665-770 of human ICAM5.
Sequence
PPEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSREGIPWPEQQRVSREDAGTYHCVATNAHGTDSRTVTVGVEYRPVVAELAASPPGGVRPGGNFTLTCR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1 - 4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50 - 1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with ICAM5 polyclonal antibody (Cat # PAB30568) shows distinct positivity in neuropil.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with ICAM5 polyclonal antibody (Cat # PAB30568) shows positivity in nucleus but excluded from the nucleoli. Antibody staining is shown in green. -
Gene Info — ICAM5
Entrez GeneID
7087Protein Accession#
Q9UMF0Gene Name
ICAM5
Gene Alias
TLCN, TLN
Gene Description
intercellular adhesion molecule 5, telencephalin
Omim ID
601852Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq
Other Designations
intercellular adhesion molecule 5|telencephalin
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Interactome
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Disease
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