AKAP9 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human AKAP9.
Immunogen
Recombinant protein corresponding to amino acids 963-1110 of human AKAP9.
Sequence
EKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1 - 4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with AKAP9 polyclonal antibody (Cat # PAB30559) shows strong cytoplasmic positivity in exocrine glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with AKAP9 polyclonal antibody (Cat # PAB30559) shows positivity in the Golgi apparatus and centrosome. Antibody staining is shown in green. -
Gene Info — AKAP9
Entrez GeneID
10142Protein Accession#
Q99996Gene Name
AKAP9
Gene Alias
AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, MU-RMS-40.16A, PRKA9, YOTIAO
Gene Description
A kinase (PRKA) anchor protein (yotiao) 9
Omim ID
604001Gene Ontology
HyperlinkGene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq
Other Designations
A-kinase anchor protein 9|A-kinase anchor protein, 350kDa|A-kinase anchoring protein 450|AKAP120-like protein|AKAP9-BRAF fusion protein|centrosome- and golgi-localized protein|kinase N-associated protein|protein kinase A anchoring protein 9
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Interactome
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Disease
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