ACVR1C polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with ACVR1C polyclonal antibody (Cat # PAB30418) shows strong cytoplasmic positivity in glandular cells at 1:20-1:50 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human ACVR1C.
Immunogen
Recombinant protein corresponding to human ACVR1C.
Sequence
ELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with ACVR1C polyclonal antibody (Cat # PAB30418) shows strong cytoplasmic positivity in glandular cells at 1:20-1:50 dilution. -
Gene Info — ACVR1C
Entrez GeneID
130399Protein Accession#
Q8NER5Gene Name
ACVR1C
Gene Alias
ACVRLK7, ALK7
Gene Description
activin A receptor, type IC
Omim ID
608981Gene Ontology
HyperlinkGene Summary
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
Other Designations
activin receptor-like kinase 7
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Interactome
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Pathway
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Disease
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