ACCN3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human kidney tissue lysate with ACCN3 polyclonal antibody (Cat # PAB29970) at 2.5 ug/mL working concentration.
Western Blot (Tissue lysate)
Western Blot analysis of human fetal lung tissue lysate with ACCN3 polyclonal antibody (Cat # PAB29970) at 1 ug/mL working concentration.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with ACCN3 polyclonal antibody (Cat # PAB29970) at 4-8 ug/mL working concentration.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human ACCN3.
Immunogen
A synthetic peptide corresponding to N-terminus of human ACCN3.
Sequence
VATFLYQVAERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRSRL
Host
Rabbit
Theoretical MW (kDa)
58
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-8 ug/mL)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (2% sucrose, 0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human kidney tissue lysate with ACCN3 polyclonal antibody (Cat # PAB29970) at 2.5 ug/mL working concentration.Western Blot (Tissue lysate)
Western Blot analysis of human fetal lung tissue lysate with ACCN3 polyclonal antibody (Cat # PAB29970) at 1 ug/mL working concentration.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with ACCN3 polyclonal antibody (Cat # PAB29970) at 4-8 ug/mL working concentration. -
Gene Info — ACCN3
Entrez GeneID
9311GeneBank Accession#
NM_004769Protein Accession#
NP_004760;Q9UHC3Gene Name
ACCN3
Gene Alias
ASIC3, DRASIC, SLNAC1, TNaC1
Gene Description
amiloride-sensitive cation channel 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
amiloride-sensitive cation channel 3, testis|modulatory subunit of ASIC2a|proton-gated cation channel subunit|testis sodium channel 1
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Interactome
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Disease
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