DYRK3 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of DYRK3 polyclonal antibody (Cat # PAB2930) in Jurkat cell lysate. DYRK3 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DYRK3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human DYRK3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of DYRK3 polyclonal antibody (Cat # PAB2930) in Jurkat cell lysate. DYRK3 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. -
Gene Info — DYRK3
Entrez GeneID
8444Protein Accession#
O43781Gene Name
DYRK3
Gene Alias
DYRK5, RED, REDK, hYAK3-2
Gene Description
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Omim ID
603497Gene Ontology
HyperlinkGene Summary
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000034527|OTTHUMP00000034528|OTTHUMP00000034529|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5|protein kinase Dyrk3|regulatory erythroid kinase
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Interactome
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Publication Reference
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[Molecular cloning and characterization of novel protein kinase gene DYRK3].
Xia J, Yang X, Ruan Q, Pan Q, Liu C, Xie W, Deng H.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 1998 Dec; 15(6):327.
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Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.
Becker W, Weber Y, Wetzel K, Eirmbter K, Tejedor FJ, Joost HG.
The Journal of Biological Chemistry 1998 Oct; 273(40):25893.
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[Molecular cloning and characterization of novel protein kinase gene DYRK3].
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