UNG polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of UNG in NIH/3T3 cell lysate with UNG polyclonal antibody (Cat # PAB27429) at 1 ug/mL in (lane 1) the presence and (lane 2) the absence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UNG.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human UNG.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
At least two isoforms of UNG2 are known to exist; this antibody will only detect the longer isoform. UNG2 antibody is predicted to not cross-react with UNG1.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of UNG in NIH/3T3 cell lysate with UNG polyclonal antibody (Cat # PAB27429) at 1 ug/mL in (lane 1) the presence and (lane 2) the absence of blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — UNG
Entrez GeneID
7374Protein Accession#
NP_550433Gene Name
UNG
Gene Alias
DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
Gene Description
uracil-DNA glycosylase
Gene Ontology
HyperlinkGene Summary
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. [provided by RefSeq
Other Designations
uracil-DNA glycosylase 1, uracil-DNA glycosylase 2|uracil-DNA glycosylase 2
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Interactome
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Pathway
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Disease
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