CELSR1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human tonsil (A), human adrenal gland (B), human kidney (C) and human testis (D) with CELSR1 polyclonal antibody (Cat # PAB26153).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CELSR1.
Immunogen
A synthetic peptide corresponding to 17 amino acids at N-terminus of human CELSR1.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CELSR3 (47%).
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human tonsil (A), human adrenal gland (B), human kidney (C) and human testis (D) with CELSR1 polyclonal antibody (Cat # PAB26153).Enzyme-linked Immunoabsorbent Assay
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Gene Info — CELSR1
Entrez GeneID
9620Protein Accession#
Q9NYQ6Gene Name
CELSR1
Gene Alias
CDHF9, DKFZp434P0729, FMI2, HFMI2, ME2
Gene Description
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
Omim ID
604523Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000028852|cadherin EGF LAG seven-pass G-type receptor 1|protocadherin flamingo 2
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Interactome
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Disease
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