KIAA0196 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of KIAA0196 in human ovary tissue with KIAA0196 polyclonal antibody (Cat # PAB25762) at 1 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KIAA0196.
Immunogen
A synthetic peptide corresponding to 19 amino acids at C-terminus of human KIAA0196.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Multiple isoforms of Strumpellin are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of KIAA0196 in human ovary tissue with KIAA0196 polyclonal antibody (Cat # PAB25762) at 1 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KIAA0196
Entrez GeneID
9897Protein Accession#
NP_055661Gene Name
KIAA0196
Gene Alias
MGC111053, SPG8
Gene Description
KIAA0196
Gene Ontology
HyperlinkGene Summary
This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases. [provided by RefSeq
Other Designations
spastic paraplegia 8 (autosomal dominant)|strumpellin
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Interactome
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Disease
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