SULT1A1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SULT1A1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human SULT1A1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The SULT1A1 polyclonal antibody (Cat # PAB2532) is used in Western blot to detect SULT1A1 in mouse kidney tissue lysate. -
Gene Info — SULT1A1
Entrez GeneID
6817Protein Accession#
NP_001046Gene Name
SULT1A1
Gene Alias
HAST1/HAST2, MGC131921, MGC5163, P-PST, PST, ST1A3, STP, STP1, TSPST1
Gene Description
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
Omim ID
171150Gene Ontology
HyperlinkGene Summary
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000162569|aryl sulfotransferase|phenol-preferring phenol sulfotransferase1|phenol-sulfating phenol sulfotransferase|thermostable phenol sulfotransferase1
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Adenoma
- Asthma
- Brain Neoplasms
- Breast cancer
- Breast Diseases
- Breast Neoplasms
- Carcinoma
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Publication Reference
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Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3.
Barnett AC, Tsvetanov S, Gamage N, Martin JL, Duggleby RG, McManus ME.
The Journal of Biological Chemistry 2004 Feb; 279(18):18799.
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Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study.
Zheng L, Wang Y, Schabath MB, Grossman HB, Wu X.
Cancer Letters 2003 Dec; 202(1):61.
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A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.
Liang G, Miao X, Zhou Y, Tan W, Lin D.
Carcinogenesis 2003 Dec; 25(5):773.
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Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3.
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