DEFA4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human heart tissue using DEFA4 polyclonal antibody (Cat # PAB25165).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DEFA4.
Immunogen
A synthetic peptide corresponding to DEFA4.
Host
Rabbit
Reactivity
Human
Specificity
DEFA4 polyclonal antibody detects endogenous levels of DEFA4 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human heart tissue using DEFA4 polyclonal antibody (Cat # PAB25165). -
Gene Info — DEFA4
Entrez GeneID
1669Gene Name
DEFA4
Gene Alias
DEF4, HNP-4, HP-4, HP4, MGC120099, MGC138296
Gene Description
defensin, alpha 4, corticostatin
Omim ID
601157Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq
Other Designations
corticostatin|defensin, alpha 4|defensin, alpha 4, preproprotein
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Disease
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