CHRD polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis in mouse bladder tissue lysates (35 ug/lane) with CHRD polyclonal antibody (Cat # PAB2497).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CHRD.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CHRD.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis in mouse bladder tissue lysates (35 ug/lane) with CHRD polyclonal antibody (Cat # PAB2497). -
Gene Info — CHRD
Entrez GeneID
8646Protein Accession#
NP_003732;Q9H2X0Gene Name
CHRD
Gene Alias
MGC133038
Gene Description
chordin
Omim ID
603475Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000180571
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Interactome
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Pathway
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Disease
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Publication Reference
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A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Lim J, Hao T, Shaw C, Patel AJ, Szabo G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabasi AL, Vidal M, Zoghbi HY.
Cell 2006 May; 125(4):801.
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Chordin is underexpressed in ovarian tumors and reduces tumor cell motility.
Moll F, Millet C, Noel D, Orsetti B, Bardin A, Katsaros D, Jorgensen C, Garcia M, Theillet C, Pujol P, Francois V.
FASEB Journal 2006 Feb; 20(2):240.
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A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
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