GABRE polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with GABRE polyclonal antibody (Cat # PAB24461) shows strong cytoplasmic positivity in renal tubules at 1:500-1:1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GABRE.
Immunogen
Recombinant protein corresponding to amino acids of human GABRE.
Sequence
PQTESKNEASSRDVVYGPQPQPLENQLLSEETKSTETETGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEIAVNSLGPL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with GABRE polyclonal antibody (Cat # PAB24461) shows strong cytoplasmic positivity in renal tubules at 1:500-1:1000 dilution. -
Gene Info — GABRE
Entrez GeneID
2564Protein Accession#
P78334Gene Name
GABRE
Gene Alias
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Gene Description
gamma-aminobutyric acid (GABA) A receptor, epsilon
Omim ID
300093Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq
Other Designations
GABA(A) receptor|OTTHUMP00000025892
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Interactome
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Pathway
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Disease
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Publication Reference
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Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
Neman J, Termini J, Wilczynski S, Vaidehi N, Choy C, Kowolik CM, Li H, Hambrecht AC, Roberts E, Jandial R.
PNAS 2014 Jan; 111(3):984.
Application：IF, Human, Breast cancer.
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Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
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