OAS3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OAS3.
Immunogen
Recombinant protein corresponding to amino acids of human OAS3.
Sequence
TWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGCSGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with OAS3 polyclonal antibody (Cat # PAB23793) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with OAS3 polyclonal antibody (Cat # PAB23793) shows strong cytoplasmic and membranous positivity in cells in tubules at 1:500-1:1000 dilution. -
Gene Info — OAS3
Entrez GeneID
4940Protein Accession#
Q9Y6K5Gene Name
OAS3
Gene Alias
MGC133260, p100
Gene Description
2'-5'-oligoadenylate synthetase 3, 100kDa
Omim ID
603351Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq
Other Designations
2'-5'-oligoadenylate synthetase 3 (100 kD)|2'-5'oligoadenylate synthetase 3|2'-5'oligoadenylate synthetase p100
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Interactome
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Disease
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