Products

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human liver with GFER polyclonal antibody (Cat # PAB23772) shows strong cytoplasmic positivity in hepatocytes at 1:50-1:200 dilution.

Immunofluorescence

Immunofluorescent staining of human cell line U-2 OS with GFER polyclonal antibody (Cat # PAB23772) at 1-4 ug/mL dilution shows positivity in cytoplasm and mitochondria.

Entrez GeneID

2671

Protein Accession#

P55789

Gene Name

GFER

Gene Alias

ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS

Gene Description

growth factor, augmenter of liver regeneration

Omim ID

600924

Gene Ontology

Hyperlink

Gene Summary

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq

Other Designations

ERV1 homolog|augmenter of liver regeneration|erv1-like growth factor|hepatic regenerative stimulation substance|hepatopoietin protein|truncated augmenter of liver regeneration