PPP1R3D polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with PPP1R3D polyclonal antibody (Cat # PAB23755) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PPP1R3D.
Immunogen
Recombinant protein corresponding to amino acids of human PPP1R3D.
Sequence
ELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPPPVEAADFGERLQRQLVCLERVTCSDL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with PPP1R3D polyclonal antibody (Cat # PAB23755) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution. -
Gene Info — PPP1R3D
Entrez GeneID
5509Protein Accession#
O95685Gene Name
PPP1R3D
Gene Alias
DKFZp781L2441, PPP1R6
Gene Description
protein phosphatase 1, regulatory (inhibitor) subunit 3D
Omim ID
603326Gene Ontology
HyperlinkGene Summary
Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. This gene encodes a glycogen-targeting subunit of PP1. [provided by RefSeq
Other Designations
OTTHUMP00000031436|protein phosphatase 1, regulatory subunit 3D|protein phosphatase 1, regulatory subunit 6, spinophilin
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Interactome
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Pathway
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