GNB1L polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GNB1L.
Immunogen
Recombinant protein corresponding to amino acids of human GNB1L.
Sequence
VDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDEVQILEMPSKTSVCALKPKADAKLGMPMCLRLWQADCSSRPLLLAGYEDGSVVL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with GNB1L polyclonal antibody (Cat # PAB22629) shows moderate cytoplasmic positivity in tubular cells at 1:50-1:200 dilution. -
Gene Info — GNB1L
Entrez GeneID
54584Protein Accession#
Q9BYB4Gene Name
GNB1L
Gene Alias
DGCRK3, FKSG1, GY2, KIAA1645, WDR14, WDVCF
Gene Description
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Omim ID
610778Gene Ontology
HyperlinkGene Summary
This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene. [provided by RefSeq
Other Designations
G-protein beta subunit-like protein|guanine nucleotide binding protein beta-subunit-like polypeptide
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Interactome
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Disease
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