DACH1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DACH1.
Immunogen
Recombinant protein corresponding to amino acids of human DACH1.
Sequence
PKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVKKIKLEAMSNYHASNNQHGADSENGDMNSSVGSSDGSWDKETLPSSPSQGPQASITHPRMPGARSLPLSHPLNHLQQSHLLPNGLELP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with DACH1 polyclonal antibody (Cat # PAB20612) shows strong nuclear positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with DACH1 polyclonal antibody (Cat # PAB20612) at 1-4 ug/mL dilution shows positivity in nucleus, nucleoli. -
Gene Info — DACH1
Entrez GeneID
1602Protein Accession#
Q9UI36Gene Name
DACH1
Gene Alias
DACH, FLJ10138
Gene Description
dachshund homolog 1 (Drosophila)
Omim ID
603803Gene Ontology
HyperlinkGene Summary
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000018493|OTTHUMP00000040839|dachshund homolog 1
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Interactome
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Disease
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