SDC1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SDC1 polyclonal antibody (Cat # PAB20340) shows distinct positivity of plasma cells at 1:50-1:200 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SDC1 polyclonal antibody (Cat # PAB20340) at 1-4 ug/mL dilution shows positivity in focal adhesions.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SDC1.
Immunogen
Recombinant protein corresponding to amino acids of human SDC1.
Sequence
TTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human lymph node with SDC1 polyclonal antibody (Cat # PAB20340) shows distinct positivity of plasma cells at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with SDC1 polyclonal antibody (Cat # PAB20340) at 1-4 ug/mL dilution shows positivity in focal adhesions. -
Gene Info — SDC1
Entrez GeneID
6382Protein Accession#
P18827Gene Name
SDC1
Gene Alias
CD138, SDC, SYND1, syndecan
Gene Description
syndecan 1
Omim ID
186355Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq
Other Designations
CD138 antigen|OTTHUMP00000115942|heparan sulfate proteoglycan fibroblast growth factor receptor|syndecan proteoglycan 1
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Interactome
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Pathway
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Disease
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