ADAM15 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of human fetal liver tissue lysate with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:200 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human stomach showing membrane staining with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:100 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADAM15.
Immunogen
A synthetic peptide corresponding to C-terminus of human ADAM15.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Recommend Usage
ELISA (1:80000)
Western Blot (1:200-1000)
Immunohistochemistry (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human fetal liver tissue lysate with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:200 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded human stomach showing membrane staining with ADAM15 polyclonal antibody (Cat # PAB19739) at 1:100 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADAM15
Entrez GeneID
8751Protein Accession#
Q13444Gene Name
ADAM15
Gene Alias
MDC15
Gene Description
ADAM metallopeptidase domain 15
Omim ID
605548Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
OTTHUMP00000015780|a disintegrin and metalloproteinase domain 15|a disintegrin and metalloproteinase domain 15 (metargidin)|metalloprotease RGD disintegrin protein|metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15|metargidin
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Interactome
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Disease
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