HRH2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
HRH2 polyclonal antibody (Cat # PAB19657) (0.1 ug/mL) staining of human duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of HRH2.
Immunogen
A synthetic peptide corresponding to amino acids 309-323 at internal region of human HRH2.
Sequence
C-SHNSHKTSLRLNNS
Host
Goat
Theoretical MW (kDa)
44.5
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_001124527.1; NP_071640.1).
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
HRH2 polyclonal antibody (Cat # PAB19657) (0.1 ug/mL) staining of human duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — HRH2
Entrez GeneID
3274Protein Accession#
NP_001124527.1;NP_071640.1Gene Name
HRH2
Gene Alias
H2R
Gene Description
histamine receptor H2
Omim ID
142703Gene Ontology
HyperlinkGene Summary
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
gastric receptor 1
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Pathway
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Disease
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