CXCL10 polyclonal antibody
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of recombinant human CXCL10 protein with CXCL10 polyclonal antibody (Cat # PAB19527).
Lane 1, 10 ng.
Lane 2, 5 ng.
Lane 3, 2.5 ng.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human mammary cancer tissue section with CXCL10 polyclonal antibody (Cat # PAB19527).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CXCL10.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human CXCL10.
Host
Rabbit
Reactivity
Human
Specificity
It identical to the related mouse and rat sequences.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of recombinant human CXCL10 protein with CXCL10 polyclonal antibody (Cat # PAB19527).
Lane 1, 10 ng.
Lane 2, 5 ng.
Lane 3, 2.5 ng.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human mammary cancer tissue section with CXCL10 polyclonal antibody (Cat # PAB19527). -
Gene Info — CXCL10
Entrez GeneID
3627Gene Name
CXCL10
Gene Alias
C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
Gene Description
chemokine (C-X-C motif) ligand 10
Omim ID
147310Gene Ontology
HyperlinkGene Summary
This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq
Other Designations
gamma IP10|interferon-inducible cytokine IP-10|protein 10 from interferon (gamma)-induced cell line|small inducible cytokine B10|small inducible cytokine subfamily B (Cys-X-Cys), member 10
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Interactome
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Pathway
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Disease
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Publication Reference
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Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis.
Dos Santos RS, Marroqui L, Grieco FA, Marselli L, Suleiman M, Henz SR, Marchetti P, Wernersson R, Eizirik DL.
Endocrinology 2017 Aug; 158(8):2503.
Application：ELISA, Rat, INS-1E cells.
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Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.
Wennerberg E, Pfefferle A, Ekblad L, Yoshimoto Y, Kremer V, Kaminskyy VO, Juhlin CC, Hoog A, Bodin I, Svjatoha V, Larsson C, Zedenius J, Wennerberg J, Lundqvist A.
Clinical Cancer Research 2014 Nov; 20(22):5733.
Application：IHC-P, Human, Thyroid, Anaplastic thyroid carcinoma.
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Protective Role of Complement C3 Against Cytokine-Mediated β-Cell Apoptosis.
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